The Orthopaedic Spinal Research Institute

The Orthopaedic Spinal Research Institute was established in 1986 at Johns Hopkins Hospital with grant support from the National Institute of Health (NIH) and the Orthopaedic Research Education Foundation (OREF).

Our Mission

The Orthopaedic Spinal Research Institute at The University of Maryland St. Joseph Medical Center provides a basic scientific environment in which researchers, clinicians, and private industry corporations share the opportunity to pursue their orthopaedic and neurosurgical based research interests.

"It is truly our collaborative effort with both research and clinical fellows from around the world that provides innovative and advanced technology for the surgical care and treatment of spinal patients."
- Bryan W. Cunningham, PhD

Areas Of Spinal Research

The laboratory facilities are divided into three primary areas: Biomechanics, Histology and Radiography.

Using systematic and scientific methodology, the primary focus of the laboratory is to investigate the biomechanical and biological response to spinal instrumentation, and determine the optimal materials and techniques to achieve stabilization and motion preservation in the spine while providing the utmost quality of life.

Basic Scientific Research
The laboratory collaborates with neurosurgeons and spine surgeons from The Johns Hopkins Hospital, University of Maryland and other prestigious national and international institutions to address basic scientific research issues related to reconstructive spinal surgery.

FDA Pre-Clinical Studies
The laboratory is a Good Laboratory Practices (GLP) compliant facility that performs extensive FDA pre-clinical studies using in-vitro cadaveric and in-vivo animal modeling to investigate new biomechanical and biological concepts in spinal reconstructive surgery. The majority of these studies are performed for private industry on a proprietary basis to support FDA 510K and IDE applications.